I go thru hawkesbury sometimes for work, take 50 to get to north montreal are to avoid traffic going there as well as coming back so good to know I can potentially do the stop without having to use my own gas lol
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You can use many powders in a wide variety of calibres. This doesn't mean that powder will produce a good load in each of those calibres. You could be getting 3-4 MOA (or worse) groups, which in my opinion, doesn't present any advantage over factory loaded ammo for most calibres. My advice would be to decide which will be your primary calibre of interest, find out (by looking online - CGN) which powder(s) are recognized by the majority as being a really good option for your calibre and bullet weight, then try to determine if those powders are also good for some of your other calibres. If you find something that should work, give it a try. If it turns out to be a dud, well, you can go out and buy something else. Keep in mind though that preparing handloads is time consuming, so sometimes it's better just to buy the powder that is known to be great for your calibre, even if this means you end up with several different powders for all of your calibres. It can be better than wasting your time (and money on bullets) messing around with a powder that might never work well in your calibre. In summary, the magic one-size-fits-all powder may not exist, depending on the calibres you have. Based on the ones you listed, I think you will have trouble finding one that will work in all.
I don't know if there is a storefront, probably best to call ahead.
As for the best powder, as rf2 said, you may or may not have good results.
If you want to use say H4350, google it with 30-06 and with 22-250 and get a sense of what type of groups others are getting. That does not mean that it will work out or not in your gun but if a lot of people have good results then it may be efficient for your cartridge and worth the $50 to try.
Worst case with H4350, if the 22-250 does not work it is not a waste, it will work for the 30-06. The same goes with that H4895, it is not a throw away powder. There are some powders out there that are very specific, if it does not work then it collects dust, I assume you want to stay away from those.
Also looking, I remember last Christmas 2018 RCSB had a kit on sale for 100$ but doesn't even look like it's available anymore but the lee kit is still 220 and need to upgrade the scale so still not a bad deal
Higginson does have a storefront. If you want powder though, you have to call the day before at a minimum. They provide mostly bulk powder, so if you buy small quantities, don't expect to receive it in a nice little 1 lb cannister. It will come in a plastic bag in a little box. If Lee offers a kit, then Higginson probably has it. It should be in the Lee catalogue, or you can just give Higginson a call to confirm. They really have everything you would need to get into reloading, all in one place.
Just to be clear, it's a small storefront. There's not really much to look at, but the guy is able to quickly tell you what he has in stock, so he could grab you stuff from the back if you want to see something. I've been there a couple of times and mail-ordered stuff a few other times. It's a great place, but it's a bit far for me.