I grew up hearing all the "old timer" stories. My Grandfather was a founding member of the Toronto Sportsman Association. He used to chum with Greg Clark, who chumed with Hemingway. The only stories I've heard where those using a twelve gauge with 00 buck shot. I have pictures of Moose and Deer hanging in camp circa 1920's. Handguns were not used and were not considered to not be a sportsman's choice of firearm.
To use a handgun as a back-up to scare off nasties is one thing as a main firearm??? I did look up ballistics on a 44 Mag and a 357 Mag. Neither even comes close to the standard 1000ft/lbs for a deer, let alone the 1500 ft/lbs for moose.
http://www.hornady.com/store/357-Mag-140-gr-XTP/
So what would be ethical about using something undersized to humanly kill an animal?