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April 11th, 2017, 09:32 AM
#71

Originally Posted by
MikePal
I was under the impression that the Vanguard vaccine was relatively new, the published tech bulletin on it is dated 2015.
Looks like it was approved by the USDA in Jan. 2016. Availability in Canada is relatively new AFAIK
https://news.vcu.edu/article/VCU_Sch...ional_for_Lyme
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April 11th, 2017 09:32 AM
# ADS
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April 11th, 2017, 11:10 AM
#72

Originally Posted by
awndray
This vaccine was administered a few weeks ago;
The vet would have recommended a booster after 3 weeks if he got the Vanguard vaccine. I don't know if that will be a yearly thing or if it's just the first time they start on the vaccine.
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April 11th, 2017, 11:22 AM
#73
The first shot was several weeks ago. The booster was done last week. Come to think of it, I don't think it's the Lyme vaccine we're discussing here though. He's being treated with doxycycline due to the high QC6 result. Then there's Bravecto for protection.
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April 11th, 2017, 01:26 PM
#74

Originally Posted by
be2man
The Lyme Vaccines are meant to neutralize the bacteria that cause the disease, not repel ticks. The Vanguard crLyme looks to be the best vaccine technology currently available. I was able to talk to Dr Richard Marconi, the vaccine's developer, at a Conference and he assured me that the vaccine prevented dogs developing [COLOR="#FF0000"]Lyme related Arthritis and Nephritis and would also prevent dogs that were exposed to Lyme from seroconverting and testing positive on the Snap 4DX and Quant C6 tests in the future.
One of the unknowns with Lyme is how many dogs may develop subclinical arthritis and are never overtly lame, but don't perform as well as they might otherwise.
The current thinking is that even with treatment Lyme positive dogs are never completely free of the bacteria, that natural infection doesn't stimulate immunity and that dogs can get reinfected over and over again if not on a prevention program and in a Lyme endemic area.
If you live in an area where Lyme ticks are common I think the vaccine is an extra layer of protection but not a replacement for a good repellent or acaricide product.
More time will tell if this vaccine works as well in large scale use as it has in Clinical trials.
Dr Marconi is also working on a human vaccine for multiple tick borne infections.
It's surprising there's still no effective human vaccine for this serious illness that is reported to infect 300,000 people a year in the U.S. It's quite likely the development of this vaccine is a step on the road to getting a human vaccine approved.
Now that is very interesting.......... "Lyme related arthritis" .................. I've always thought my old girl had osteoarthritis, but maybe..............
" We are more than our gender, skin color, class, sexuality or age; we are unlimited potential, and can not be defined by one label." quote A. Bartlett
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April 11th, 2017, 08:19 PM
#75
My wife was the one who took our mutt to the vet so the info is coming in bits. .. The vet told her that Rev will kill the ticks (and they will stay attached until they die) so less chance of dog dropping a live tick in the house (is this a concern with other control methods? ). However, the length of time it takes for Rev to kill is not quick enough to guarantee that Lyme will not be transmitted. Apparently it takes a while for Lyme to be transmitted but the effective time of Rev (on ticks) is slightly longer than the minimum time required for a Lyme infection to be transmitted.
Again this is second hand from one vet. How does it square with what you know? Thanks.
Heeere fishy fishy fishy fishy! :fish:
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April 11th, 2017, 08:58 PM
#76
Revolution does not work for deer ticks. It's in the product info packed in the box.
Sent from my SM-T560NU using Tapatalk
"The language of dogs and birds teaches you your own language."
-- Jim Harrison (1937 - 2016)
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April 12th, 2017, 08:31 AM
#77

Originally Posted by
be2man
I don't know that Canada is against it, just hasn't been approved for sale yet. It looks like it's a slow release collar version of Advantix. When it is approved in Canada it will cost more here. Like cars, clothes, shoes, food etc. For some reason American companies figure they can charge more in Canada than they do in the States. They must figure the average Canadian is better off than the average American?
Although the anti-tick chemicals in Advantix and Soresto are both pyrethroids, they are not the same. Advantix uses permerthrin and Soresto uses flumethrin. They are both acaricidal, and both are tick repellents.
One big difference is that flumethrin is not toxic to cats, while permethrin is. This opens up the cat market for tick protection.
Both products use the neonicotinoid imidacloprid as the anti-flea chemical.
Here are a couple of studies on the Soresto collars
Evaluation of the long-term efficacy and safety of an imidacloprid 10%/flumethrin 4.5% polymer matrix collar (Seresto®) in dogs and cats naturally infested with fleas and/or ticks in multicentre clinical field studies in Europe
Efficacy of an imidacloprid/flumethrin collar against fleas, ticks and tick-borne pathogens in dogs
One thing I hadn't considered is that these collars could be good for kennels or animal shelters. The product is good for 8 months, for cats or dogs, and you could just pop the collars on the new animals for a week (or whatever the determined protocol would be) and be able to re-use the collar. No sizing a spot-on to the animal's weight, possibly over-dosing.
I think I'll be ordering a pair of collars for my dogs from the states. Otherwise, I usually just buy a pack of Powerspot from Pet value for $17. Gives me four doses of permethrin spot-on; so with both dogs I can do the whole season for about $60. Our female is small though, ~12lbs, and permethrin doesn't always agree with her so I cut back on her dose. I find that we can get ticks jumping on during the fourth week of coverage with permethrin, so I think I'v got a coverage gap of a few days sticking to the once-a-month schedule.
One collar at the start of the year would save me from the hassle of reminders and those spot-on packets.
I like the idea of Bravecto, but it is not a repellent - then again it provides even and systemic protection, is working within a few hours, and is good for 12 weeks. Tough call.
Here is a quick review article of the major product components, although flumethrin is not discussed.
Systemically and cutaneously distributed ectoparasiticides: a review of the efficacy against ticks and fleas on dogs
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April 12th, 2017, 08:50 AM
#78
For the collar to be effective for that long it has to stay on the animal. Taking it off after a week or a month means the dog is no longer protected.
"You don't own a cocker, you wear one"
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April 12th, 2017, 09:06 AM
#79

Originally Posted by
Rugger
My wife was the one who took our mutt to the vet so the info is coming in bits. .. The vet told her that Rev will kill the ticks (and they will stay attached until they die) so less chance of dog dropping a live tick in the house (is this a concern with other control methods? ). However, the length of time it takes for Rev to kill is not quick enough to guarantee that Lyme will not be transmitted. Apparently it takes a while for Lyme to be transmitted but the effective time of Rev (on ticks) is slightly longer than the minimum time required for a Lyme infection to be transmitted.
Again this is second hand from one vet. How does it square with what you know? Thanks.

Originally Posted by
welsh
Revolution does not work for deer ticks. It's in the product info packed in the box.
Sent from my SM-T560NU using Tapatalk
On the tick side, it is good only for American Dog Tick and Brown Dog Tick, but requires feeding. There are much better options on the tick side.
It is effective against fleas, heartworm, some hookworms (in cats), some roundworms, many mites and sarcoptic mange.
It is non-toxic to cats and to Ivermectin-sensitive Collies.
Last edited by mooboy76; April 12th, 2017 at 09:23 AM.
CSSA Member
CCFR Member
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April 12th, 2017, 03:38 PM
#80
Nice coupon for Bravecto, still not cheap but a bit cheaper.
http://www.bravecto.ca/files/Bravecto-Coupon-EN.pdf